A Review on the Clinicopathological Features and Management of the Celiac Disease

Authors

    Fenglan Wang, Yonglin Liu, Shuying Lou, Xiaoqin Li, Linna Wang, Fuyong Jiao, Md Rezaul Karim, Abu Taiub Mohammed Mohiuddin Chowdhury Department of Pediatrics, Shenmu County Hospital, Shaanxi, P.R. China Department of Pediatrics, Shenmu County Hospital, Shaanxi, P.R. China Department of Endocrinology, Genetics and Metabolism, Zhengzhou Children’s Hospital, Zhengzhou, P.R. China Department of Gastroenterology, Zhengzhou Children’s Hospital, Zhengzhou, P.R. China Department of Clinical Medicine, Xi’an Medical University, Xi’an, P.R. China Department of Pediatrics, Shaanxi Provincial peoples Hospital, Shaanxi, P.R. China Hubei Key Laboratory of Embryonic Stem Cell Research, Institute of Neuroscience, Hubei University of Medicine, Shiyan, P.R. China Department of Gastroenterology, First Affiliated Hospital of Xi’an Jiaotong University, Shaanxi, P.R. China

DOI:

https://doi.org/10.18063/ghl.v2i2.257

Keywords:

Celiac disease, Gluten, Tissue transglutaminase, Small intestine biopsies

Abstract

Celiac disease (CD) is a multifactorial and chronic autoimmune disease caused by the ingestion of gluten. Epidemiological studies have shown that the disease is currently becoming more common worldwide. Among the countries, North America, North Europe, and Australia have high prevalence of CD. CD is often confused with other chronic gastrointestinal tract-related diseases. Therefore, it is important to have a broad understanding of the clinicopathological features of CD. This review aims to illustrate the epidemiology, pathogenesis, clinical manifestation, and diagnosis and treatment of CD.

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Published

2020-12-09

Issue

Vol. 2 No. 2 (2020): Gastroenterology & Hepatology Letters

Section

Articles